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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIST1H1C
All Species:
13.94
Human Site:
S173
Identified Species:
30.67
UniProt:
P16403
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P16403
NP_005310.1
213
21365
S173
V
T
K
K
V
A
K
S
P
K
K
A
K
V
A
Chimpanzee
Pan troglodytes
XP_001172525
213
21376
S173
V
T
K
K
V
A
K
S
P
K
K
A
K
V
A
Rhesus Macaque
Macaca mulatta
P40286
208
22075
S182
K
G
K
Q
Q
Q
K
S
P
V
K
A
R
A
T
Dog
Lupus familis
XP_853847
290
29282
S228
V
T
K
K
V
A
K
S
P
K
K
E
K
A
A
Cat
Felis silvestris
Mouse
Mus musculus
P43274
219
21959
P173
G
A
K
K
A
K
S
P
K
K
A
K
A
T
K
Rat
Rattus norvegicus
P15865
219
21969
P173
G
A
K
K
A
K
S
P
K
K
A
K
A
T
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515094
223
22581
S175
A
T
K
K
A
T
K
S
P
R
K
T
K
T
A
Chicken
Gallus gallus
P08284
219
22026
P172
T
K
K
A
A
K
S
P
K
K
A
A
K
A
G
Frog
Xenopus laevis
P06892
210
21355
A179
K
S
P
A
K
K
T
A
V
K
P
K
V
A
A
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P02255
256
26341
P225
A
K
A
S
K
A
K
P
A
V
S
A
K
P
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P19375
205
22145
P180
K
S
T
P
K
K
T
P
K
K
A
A
A
K
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
50.7
56.9
N.A.
83.5
84
N.A.
74.4
69.4
58.6
N.A.
N.A.
42.5
N.A.
N.A.
39.4
Protein Similarity:
100
99.5
61.9
60.6
N.A.
84
84.4
N.A.
79.8
73.9
67.1
N.A.
N.A.
52.3
N.A.
N.A.
49.3
P-Site Identity:
100
100
40
86.6
N.A.
20
20
N.A.
60
26.6
13.3
N.A.
N.A.
26.6
N.A.
N.A.
13.3
P-Site Similarity:
100
100
53.3
86.6
N.A.
20
20
N.A.
66.6
26.6
26.6
N.A.
N.A.
26.6
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
19
10
19
37
37
0
10
10
0
37
55
28
37
46
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
19
10
0
0
0
0
0
0
0
0
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
28
19
73
55
28
46
55
0
37
73
46
28
55
10
37
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
10
10
0
0
0
46
46
0
10
0
0
10
0
% P
% Gln:
0
0
0
10
10
10
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
10
0
0
10
0
0
% R
% Ser:
0
19
0
10
0
0
28
46
0
0
10
0
0
0
0
% S
% Thr:
10
37
10
0
0
10
19
0
0
0
0
10
0
28
10
% T
% Val:
28
0
0
0
28
0
0
0
10
19
0
0
10
19
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _